When looking for a bed and breakfast, the general location will naturally be a leading factor in your decision. However, the smallest details of that location can make the most significant difference. Your choice should be centrally based on your plans while in the area. If a bed and breakfast is centrally located by means of accessing the city, it may be inconvenient if your trip is planned around outdoor exploring in the more scenic areas of the city or state. Be sure that your choice is close to your desired sights and activities. Your chosen bed and breakfast should also be comfortable to find, both by you and any required hired transport.
Another factor to consider is the safety of the immediate area where the bed and breakfast is located. Even in a safe city, various suburbs may be less reliable than others. Your ideal spot should be in an open and secure area so as not to put yourself at any risk. Lastly, you might want to check the views available from the location. If you are looking for a scenic experience, you can check online what the surroundings look like, from the position of the bed and breakfast, before booking.